
There are many different types of diabetes medications, each with its own unique mechanism of action. Here are some of the most common types:
- Metformin: Metformin is a commonly prescribed medication for type 2 diabetes. It works by reducing the glucose produced by the liver and improving insulin sensitivity, which helps glucose get into the cells where it can be used for energy. It is usually the first medication prescribed.
- Sulfonylureas: Sulfonylureas are a class of oral medications that stimulate the pancreas to release more insulin. They work by closing potassium channels in the beta cells of the pancreas, which causes the cells to release insulin.
- DPP-4 inhibitors: DPP-4 inhibitors are oral medications that help regulate blood sugar levels by blocking the enzyme DPP-4. This enzyme breaks down a hormone called incretin, which stimulates insulin production. By blocking DPP-4, the medication helps to increase insulin secretion and decrease the amount of glucose produced by the liver.
- GLP-1 receptor agonists: GLP-1 receptor agonists like are injectable medications that mimic the action of incretin hormones. They work by signaling the pancreas to release more insulin, while also slowing down digestion and reducing appetite. This helps to lower blood sugar levels and promote weight loss. There are GLP-1’s like Trulicity injectable taken by a number of patients.
- SGLT2 inhibitors: SGLT2 inhibitors are a newer class of oral medications that work by blocking the SGLT2 protein in the kidneys. This protein is responsible for reabsorbing glucose back into the bloodstream. By blocking SGLT2, the medication allows excess glucose to be excreted in the urine, which helps to lower blood sugar levels. The body is so fascinating.
- Insulin: Insulin is a hormone that allows glucose to enter cells and be used for energy. People with type 1 diabetes need to take insulin, as their bodies do not produce any insulin. Some people with type 2 diabetes also need to take insulin if other medications are not providing adequate control of blood sugar levels.
It’s important to note that the mechanism of action can vary within each class of medication, and there can be potential side effects for each medication. It’s always important to consult with a healthcare provider before adding any new medications to your diabetes management routine.
Take the name of the medications you are currently taking and see which of the above diabetes medication class your medications fall into. This would help you to know which organ in the body is processing those medications. Ensure to periodically ask your doctor to request blood tests to ensure your organs like the liver, kidneys are still operating optimally. Remember to look up the side effects of all of your medications. This can prompt you to look into lifestyle changes.
Mnemonic : 2liver 2 pancreas 1 kidney
Liver: Metformin & DPP4
Pancreas: Sulfonylureas & GLP-1 (Trulicity)
Kidney : SGLT2 inhibitors
Action: You can look up the names of the medications you are taking and match to above list.
Post your findings
Author: Dr Gloria Penn- Wheatley https
“Daily Diabetes Log Book:” Know your blood sugar numbers ;: